5-Diazouracil
Agent Name
5-Diazouracil
CAS Number
2435-76-9
Formula
C4-H2-N4-O2
Major Category
Other Uses
Synonyms
2,4-Diossi-5-diazopirimidina [Italian]; 2,6-Dioxo-5-diazopyrimidine; 5-Diazo-2,4(1H,3H)-pyrimidinedione; 5-Diazopyrimidine-2,4(3H)-dione; Diazouracil; 2,4(1H,3H)-Pyrimidinedione, 5-diazo- (9CI); 2,4(3H,5H)-Pyrimidinedione, 5-diazo-; [ChemIDplus] DU; 2,4-Dioxo-5-diazopyrimidine; 5-Diazo-2,4-dioxopyrimidine; [Merck Index] 5-DU; [RTECS]
Category
Biochemical Research
Description
Solid; Sensitive to light, air, and temperature; [Merck Index]
Sources/Uses
Used in cancer research; [Merck Index]
Comments
Intraperitoneal LD50 (mouse) = 30.8 mg/kg; [RTECS] A study from 1973 reported that 5-20 mg/kg administered on day 10 produced embryo lethality but no teratogenicity in mice; [Shepard's Catalog of Teratogenic Agents] May cause irritation; [Sigma-Aldrich MSDS]
Biomedical References
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.