Agent Name
CAS Number
89-82-7; 15932-80-6
Major Category
Biological Agents
Pulegone formula graphical representation
(+)-(R)-Pulegone; (+)-Pulegone; (1R)-(+)-p-Menth-4(8)-en-3-one; (R)-(+)-Pulegone; (R)-Pulegone; 1-Isopropylidene-4-methyl-2-cyclohexanone; 1-Methyl-4-isopropylidene-3-cyclohexanone; 3-Methyl-6-isopropylidenecyclohexanone; 4(8)-p-Menthen-3-one, delta-; 5-Methyl-2-(1-methylethylidene)cyclohexanone, (R)-; Pulegon; R-Pulegone; Pulegone (natural); Pulegone, d-; d-Pulegone; p-Menth-4(8)-en-3-one, (R)-(+)-; Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (5R)-; Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (R)-; Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (theta)-; Pulegone; p-Menth-4(8)-en-3-one; [ChemIDplus] (5R)-5-Methyl-2-(1-methylethylidene)cyclohexanone; R-(+)-p-Menth-4(8)-en-3-one; [Merck Index]
Plant Oils and Extracts
Liquid with a pleasant odor between peppermint and camphor; [Merck Index] Clear light brown liquid; [Sigma-Aldrich MSDS]
A natural oil in plants of the Labiatae family; [Merck Index] Used as flavoring agent or adjuvant; [FDA] Also used in dental products, as fragrance agents, and in herbal medicines; [NTP]
All early deaths in 2-week oral studies of rats and mice at doses >300 mg/kg attributed to liver toxicity; Non-neoplastic lesions of the liver, kidney, nose, and forestomach of rats and mice observed in 2-year oral studies; Evidence for carcinogenic activity: None in male rats; some in female rats; clear evidence (liver neoplasms) in male and female mice; [NTP] Safe when used as a flavoring agent in food; [JECFA] May cause irritation; May be harmful if swallowed or inhaled; [Sigma-Aldrich MSDS]
Biomedical References

Exposure Assessment

Vapor Pressure
138 mm Hg

Adverse Effects

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Other Information
No other related information on this agent was found.