Mipafox

Agent Name
Mipafox
CAS Number
371-86-8
Formula
C6-H16-F-N2-O-P
Major Category
Pesticides
Mipafox formula graphical representation
Synonyms
Bis(isopropylamido) fluorophosphate; Bis(isopropylamido)fluorophosphate; Bis(monoisopropylamino)fluorophosphate; Bis(monoisopropylamino)fluorophosphine oxide; Bisisopropylaminofluorophosphine oxide; Di(isopropylamido)phosphoryl fluoride; Fluorobisisopropylaminophosphine oxide; Fluorure de N,N'-diisopropyle phosphorodiamide [French]; Isopestox; Mipafox [ISO]; N,N'-Diisopropil-fosforodiammido-fluoruro [Italian]; N,N'-Diisopropyl-diamido-fosforzuur-fluoride [Dutch]; N,N'-Diisopropyl-diamido-phosphorsaeure-fluorid [German]; N,N'-Diisopropyldiamidophosphoryl fluoride; N,N'-Diisopropylphosphorodiamidic fluoride; Peston XV; Pestox 15; Pestox XV; Phosphine oxide, fluorobis(isopropylamino)-; Phosphorodi(isopropylamidic) fluoride; Phosphorodiamidic fluoride, N,N'-bis(1-methylethyl)-; Phosphorodiamidic fluoride, N,N'-diisopropyl-; [ChemIDplus]
Category
Organophosphate Insecticides
Description
Odorless crystals; [HSDB]
Sources/Uses
Used as an insecticide; [Merck Index] Used in neurotoxicology studies; [HSDB]
Comments
A small number of the organophosphates (OPs) can Induce Delayed Neuropathy (OPIDN). OPIDN usually occurs after ingestion and is usually nonoccupational. [Levy, p. 431] Immediate and delayed neurotoxic effects observed in experimental animals; [HSDB] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]
Restricted
Not used in the US; [HSDB] "This chemical ingredient is not found in any products." [NPIRS]
Biomedical References

Exposure Assessment

BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Vapor Pressure
0.001 mm Hg

Adverse Effects

Neurotoxin
Predominantly motor
Other Poison
Organophosphate

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: