Mipafox

Synonyms

Bis(isopropylamido) fluorophosphate; Bis(isopropylamido)fluorophosphate; Bis(monoisopropylamino)fluorophosphate; Bis(monoisopropylamino)fluorophosphine oxide; Bisisopropylaminofluorophosphine oxide; Di(isopropylamido)phosphoryl fluoride; Fluorobisisopropylaminophosphine oxide; Fluorure de N,N'-diisopropyle phosphorodiamide [French]; Isopestox; Mipafox [ISO]; N,N'-Diisopropil-fosforodiammido-fluoruro [Italian]; N,N'-Diisopropyl-diamido-fosforzuur-fluoride [Dutch]; N,N'-Diisopropyl-diamido-phosphorsaeure-fluorid [German]; N,N'-Diisopropyldiamidophosphoryl fluoride; N,N'-Diisopropylphosphorodiamidic fluoride; Peston XV; Pestox 15; Pestox XV; Phosphine oxide, fluorobis(isopropylamino)-; Phosphorodi(isopropylamidic) fluoride; Phosphorodiamidic fluoride, N,N'-bis(1-methylethyl)-; Phosphorodiamidic fluoride, N,N'-diisopropyl-; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Odorless crystals; [HSDB]

Sources/Uses

Used as an insecticide; [Merck Index] Used in neurotoxicology studies; [HSDB]

Comments

A small number of the organophosphates (OPs) can Induce Delayed Neuropathy (OPIDN). OPIDN usually occurs after ingestion and is usually nonoccupational. [Levy, p. 431] Immediate and delayed neurotoxic effects observed in experimental animals; [HSDB] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Not used in the US; [HSDB] "This chemical ingredient is not found in any products." [NPIRS]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

0.001 mm Hg

Predominantly motor

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)