3,3'-Dimethylbenzidine dihydrochloride
Agent Name
3,3'-Dimethylbenzidine dihydrochloride
Alternative Name
o-Tolidine dihydrochloride
CAS Number
612-82-8
Formula
C14-H16-N2.2Cl-H
Major Category
Nitrogen Compounds
Synonyms
o-Tolidine dihydrochloride; 4,4'-Diamino-3,3'-dimethylbiphenyl dihydrochloride; (1,1'-Biphenyl)-4,4'-diamine, 3,3'-dimethyl-, dihydrochloride; (1,1'-Biphenyl)-4,4'-diamine, 3,3'-dimethyl-, hydrochloride (1:2); 4,4'-Bi-o-toluidine dihydrochloride; Benzidine, 3,3'-dimethyl-, dihydrochloride; [ChemIDplus] DMB-2HCl; DMB dihydrochloride; [NTP]
Category
Amines, Polyaromatic
Description
Light tan solid; [CAMEO] Light red powder; Hygroscopic; [Sigma-Aldrich MSDS]
Sources/Uses
o-Tolidine: Used to make dyes; Also used as a reagent to detect gold and free chlorine in water; [Merck Index]
Comments
Causes other endocrine changes and weight loss in 14-day oral studies of rats; Causes changes in thymus weight, bone marrow, and erythrocyte counts in 13-week oral studies of rats; [RTECS] May cause irritation; Targets the liver, kidney, and GI tract; Harmful by ingestion; [Sigma-Aldrich MSDS] See "o-Tolidine."
Biomedical References
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
NTP Carcinogen
Anticipated human carcinogen
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.