Agent Name
alpha-Naphthoflavone
Major Category
Other Uses
Synonyms
2-Phenyl-4H-naphtho(1,2-b)pyran-4-one; 7,8-BF; 7,8-Benzoflavone; Benzo(h)flavone; alpha-Naphthylflavone; 2-Phenylbenzo(h)chromen-4-one; 4H-Naphtho(1,2-b)pyran-4-one, 2-phenyl-; [ChemIDplus]
Category
Biochemical Research
Description
Solid; [Sigma-Aldrich MSDS]
Sources/Uses
"alpha-Naphthoflavone is a potent inhibitor of the enzyme aromatase, the enzyme that converts testosterone to estrogen. alpha-Naphthoflavone has been shown to cause abnormal testicular development in young chickens." [Wikipedia]
Comments
Causes lung changes, liver changes, thyroid hypofunction, and multiple enzyme effects in acute intraperitoneal studies of rats; [RTECS] May cause irritation; [Sigma-Aldrich MSDS]
Other Information
No other related information on this agent was found.