Lead chromate

Agent Name
Lead chromate
CAS Number
7758-97-6
Formula
Cr-O4.Pb
Major Category
Metals
Synonyms
Chrome yellow; C.I. Pigment yellow; [ACGIH]
Category
Lead Compounds, Inorganic
Description
Bright yellow solid; Low water solubility (5.8 ug/L); [ACGIH]
Sources/Uses
Used as a pigment; Chrome yellow is PbCrO4. Chrome green and chrome red also contain PbCrO4. [ACGIH] Used as a pigment in paints, ceramics, rubber and plastics, and fabric printing; [HSDB]
Comments
“Despite the limited evidence for lead chromate causing cancer in humans, there is ample evidence in humans and animals that all Cr(VI) compounds, both soluble and insoluble, are capable of causing lung cancer.” Lead poisoning can occur in exposed workers. [ACGIH] See "Lead" and linked occupational diseases. "See "Chromium" and linked occupational diseases.
Restricted
In 1977 the Consumer Product Safety Commission banned "lead containing paint" prohibiting the use of such paint on products to which consumers are exposed after sale. [ATSDR ToxFAQs, Toxicological Profile, Regulations and Advisories]
Biomedical References

Exposure Assessment

BEI
Lead in blood = 200 ug/L (20 ug/100 ml); sampling time not critical; [ACGIH] See "Chromium" for BEI of chromium (VI) water-soluble fume.
Skin Designation (ACGIH)
Insufficient data
Bioaccumulates
Yes
TLV (ACGIH)
0.0002 mg/m3, as Cr(VI), inhalable particulate matter
STEL (ACGIH)
0.0005 mg/m3, as Cr(VI), inhalable particulate matter
Explanatory Notes
Melting point = 844 deg C; [ACGIH]

Adverse Effects

Skin Sensitizer
Yes
Asthma
Yes
Neurotoxin
Predominantly motor
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Nephrotoxin
Yes
Reproductive Toxin
Yes
Dermatotoxin
Skin burns
IARC Carcinogen
Established
NTP Carcinogen
Human carcinogen
ACGIH Carcinogen
Confirmed Human

Diseases, Processes, and Activities Linked to This Agent

Diseases
Processes