Dinocap

Synonyms

Arathane; 2-Butenoic acid, 2-(1-methylheptyl)-4,6-dinitrophenyl ester; 2-Butenoic acid, 2(or 4)-isooctyl-4,6(or 2,6)-dinitrophenyl ester; Caprane; Capyldinitrophenyl crotonate; Caratan; Carathane; CR 1639; Crotonic acid, 2,4-dinitro-6-(1-methylheptyl)phenyl ester; Crotonic acid, 2,4-dinitro-6-(2-octyl)phenyl ester; Crotonic acid, 2-(1-methylheptyl)-4,6-dinitrophenyl ester; Crotothane; Dinitrocarylphenyl crotonate; 4,6-Dinitro-2-(2-capryl)phenyl crotonate; 2,4-Dinitro-6-(1-methylheptyl)phenyl crotonate; 4,6-Dinitro-2-(1-methylheptyl)phenyl crotonate; Dinitromethylheptylphenyl crotonate; DPC; Isocothane; Karatan; Karathane; 2-(1-Methylheptyl)-4,6-dinitrophenyl crotonate; Mildex; [HSDB]

Category

Herbicides, Nitroaromatic

Description

Dark, reddish-brown liquid; [EXTOXNET]

Sources/Uses

Nitrophenolic and nitrocresolic herbicides are used in some parts of the world as acaricides, nematicides, ovicides, and fungicides. "Only dinocap continues to have active registrations in the United States." [EPA Pesticides, p. 104] Control of mites on apples trees is the main application of dinocap in the United States. It is also used to kill powdery mildew on fruits, vegetables, and trees. [EXTOXNET]

Comments

The pathophysiology, like that of pentachlorophenol, involves the uncoupling of oxidative phosphorylation. Yellow stains appear on the skin after dermal contact with the nitroaromatic herbicides. Fatal poisoning can occur after dermal absorption. Cataracts have been reported in animal experiments and after occupational exposure. In severe poisoning, these herbicides can cause injury to the liver and kidneys. [EPA Pesticides, p. 104-5] Dinocap is a potential skin sensitizer and reproductive toxin. [EXTOXNET]

Reference Link #1

Biomedical References

4E-08 mm Hg

Explanatory Notes

VP from HSDB;

Reference Link #2

Yes

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Yes

Other Poison

Uncoupler

Diseases

Occupational diseases associated with exposure to this agent:

• Acute tubular necrosis
• Cataract, chemical or radiation induced
• Contact dermatitis, allergic
• Pentachlorophenol/Dinitrophenol, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)