Agent Name
beta-Cyclodextrin
Major Category
Biological Agents
Synonyms
Betadex; Cycloheptaamylose; Cycloheptaglucan; Cycloheptaglucosan; Cyclomaltoheptaose; Dextrin, beta-cyclo; Kleptose; Kleptose B; Rhodocap N; Ringdex B; Ringdex BL; Schardinger beta-dextrin; beta-Cycloamylose; beta-Cycloheptaamylose; beta-Dextrin; Cycloheptapentylose; [ChemIDplus] betaCD; BCD; beta-Schardinger dextrin; Cyclodextrin C; [JECFA]
Description
White virtually odorless solid; [JECFA] White powder; [Sigma-Aldrich MSDS]
Sources/Uses
Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used as flavoring agent and formulation aid; [FDA] Used as a thickening agent and an encapsulation agent for food additives, flavoring, and vitamins; [JECFA]
Comments
Composed of 7 glucose units joined together; Acceptable daily intake (ADI) of 0-5 mg/kg; [JECFA] Causes zonal hepatitis and acute tubular necrosis in 52-week constant oral studies of rats; Causes diffuse and zonal hepatitis in 7-week constant oral studies of rats; [RTECS] Causes mild skin and eye irritation in rabbits; Not a skin sensitizer in guinea pigs; [Sigma-Aldrich MSDS] See "alpha-Cyclodextrin."
Lethal Concentration
LC50 (rat) > 4,900 mg/m3/4hr
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Other Information
No other related information on this agent was found.