Buthionine sulfoximine
Agent Name
Buthionine sulfoximine
CAS Number
5072-26-4
Formula
C8-H18-N2-O3-S
Major Category
Other Uses
Synonyms
2-Amino-4-(S-butylsulfonimidoyl)butanoic acid; Buthione sulfoximine; Buthionine sulfoxamine; Buthionine sulphoximine; Butionine sulfoximine; Sulfoximine, S-(3-amino-3-carboxypropyl)-S-butyl-; Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-; [ChemIDplus] S-(3-Amino-3-carboxypropyl)-S-butylsulfoximine; S-(-n-Butyl)homocysteine sulfoximine; BSO; [Merck Index]
Category
Biochemical Research
Description
Solid; [Merck Index]
Sources/Uses
Used as a "biological tool for depletion of glutathione"; [Merck Index]
Comments
Causes lung changes, effects on lipids and proteins, liver changes, and maternal reproductive effects in acute intraperitoneal studies of rats; Causes diffuse hepatitis in 2-week intermittent subcutaneous studies of guinea pigs; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS]
Biomedical References
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.