Diglycidyl ether

Synonyms

DGE; 1,2,6,7-Diepoxy-4-oxaheptane; Bis(2,3-epoxy-1 propyl) ether; Bis(2,3-epoxypropyl) ether; DGE; Di(2,3-epoxy)propyl ether; Diallyl Ether Dioxide; Diepoxy propyl ether; Diglycidyl ether; Ether, bis(2,3-epoxypropyl); Ether, diglycidyl; Glycidyl ether; [ChemIDplus]

Category

Glycidyl Ethers

Description

Colorless liquid with a strong, irritating odor; [NIOSH]

Sources/Uses

DGE is used in epoxy resins; it is also used to treat textiles and to stabilize chlorinated organic compounds. [ACGIH]

Comments

The TLV is based on male reproductive effects and irritation to the skin and eyes. Male rats develop reproductive toxicity after 60 4-hour exposures to 0.3 ppm. High concentrations induce CNS depression in experimental animals. In the past, some workers developed slow healing burns. [ACGIH] Severely irritating to the respiratory tract and may cause pulmonary edema; May cause skin sensitization; [ICSC]

Biomedical References

Insufficient data

0.01 ppm

Ceiling(OSHA) = 0.5 ppm

10 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the male mouse 4­hour LC50 of 30 ppm [Hine et al. 1956]. . . . Human data: None relevant for use in determining the revised IDLH.

2.9 mm Hg

5 ppm

LC50 (rat) = 200 ppm/4H

Explanatory Notes

An odor threshold has not been established, but DGE is recognizable by odor above 5 ppm; [ACGIH] Flash point = 64 deg C; VP from HSDB;

Yes

Yes

Yes

Skin burns

Not Classifiable

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing
• Textiles (Printing, Dyeing, or Finishing)

Activities

Activities with risk of exposure:

• Sculpturing plastics