Campesterol
Agent Name
Campesterol
CAS Number
474-62-4
Formula
C28-H48-O
Major Category
Biological Agents
Synonyms
(24R)-5-Ergosten-3beta-ol; 24-Methylcholesterol; 24alpha-Methylcholesterol; Campesterin; delta5-24-Isoergosten-3beta-ol; (24R)-Ergost-5-en-3beta-ol; Ergost-5-en-3-ol, (3beta,24R)-; Ergost-5-en-3beta-ol, (24R)- (8CI); [ChemIDplus] (3beta,24R)-Ergost-5-en-3-ol; [Merck Index] 24alpha-Methyl-5-cholesten 3beta-ol; 24(R)-Ergost-5-en-3beta-ol; [Sigma-Aldrich MSDS]
Category
Plant Oils and Extracts
Description
Solid; [Merck Index] White crystalline solid; [Sigma-Aldrich MSDS]
Sources/Uses
Present in rape-seed oil, soybean oil, and wheat germ oil; [Merck Index] Added to food as a source of phytosterols (for blood cholesterol lowering properties); [JECFA]
Comments
Phytosterol esters containing 26-29% campesterol demonstrate no significant adverse effects in a 90-day oral study of rats; Phytosterol esters containing 27.9% campesterol produced decreased body weights, increased frequency of cardiomyopathy (males), and changes in hematology parameters in a 13-week oral study of rats at the highest tested dose (9,000 mg/kg/day); Phytosterol esters show no evidence of reproductive or developmental toxicity in rats; [JECFA] A moderate irritant; Harmful by ingestion, inhalation, and skin absorption; Targets the eyes, kidney, liver, and heart; [Sigma-Aldrich MSDS]
Biomedical References
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.