CHAPS
Agent Name
CHAPS
CAS Number
75621-03-3
Formula
C32-H58-N2-O7-S
Major Category
Other Uses
Synonyms
Cholamidopropyl)dimethylammonium)-1-propanesulfonate; 1-Propanaminium, N,N-dimethyl-3-sulfo-N-(3-(((3alpha,5beta,7alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)propyl)-,hydroxide, inner salt; 3-((3-Cholamidopropyl)dimethylammonio)-1-propanesulfonate; 1-Propanaminium, N,N-dimethyl-N-(3-sulfopropyl)-3-(((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)-, hydroxide, inner salt; [ChemIDplus] N,N-Dimethyl-N-(3-sulfopropyl)-3-[[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-1-propanaminium inner salt; [Merck Index]
Category
Biochemical Research
Description
Solid; [Merck Index] White crystalline powder; [Amresco MSDS]
Sources/Uses
Used as a non-denaturing biological detergent; [Merck Index] "CHAPS is a zwitterionic detergent used in the laboratory to solubilize biological macromolecules such as proteins. It is used as a non-denaturing solvent in the process of protein purification and is especially useful in purifying membrane proteins, which are often sparingly soluble or insoluble in aqueous solution due to their native hydrophobicity." [Wikipedia]
Comments
A skin and strong eye irritant; [Amresco MSDS]
Biomedical References
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.