Agent Name
Concanavalin A
Major Category
Other Uses
Synonyms
CON A; Concanavaline A; Ricin-toxin con A; [ChemIDplus] ConA; [Merck Index]
Category
Biochemical Research
Description
Lyophilized powder; [Sigma-Aldrich MSDS]
Sources/Uses
A plant protein in the lectin family; Isolated from jack beans; Used as a biochemical reagent and as a probe in cell biology (membrane dynamics and cell division); [Merck Index]
Comments
Teratogenic effects observed in rabbits (intraperitoneal) and mice (intravenous) exposed during gestation; [Shepard's Catalog of Teratogenic Agents] Causes diffuse hepatitis and changes in thymus and spleen weights in acute intravenous studies of mice; Causes decreased cellular immune response in 30-day intermittent intraperitoneal studies of mice; [RTECS] May cause irritation; May cause skin and respiratory sensitization; May cause toxicity to human reproduction; [Sigma-Aldrich MSDS] PubMed: no results for 11028-71-0 AND (allergic OR sensitizer OR sensitization OR asthma)[Title];
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Other Information
No other related information on this agent was found.