Iodochlorhydroxyquin

Agent Name
Iodochlorhydroxyquin
Alternative Name
Clioquinol
CAS Number
130-26-7
Formula
C9-H5-Cl-I-N-O
Major Category
Other Uses
Synonyms
Clioquinol; 5-Chloro-7-iodo-8-hydroxyquinoline; 5-Chloro-7-iodo-8-quinolinol; 5-Chloro-8-hydroxy-7-iodoquinoline; Chloroiodoquin; Chlorojodochin; Cifoform; Dioquinol; Quin-O-Creme; 7-Iodo-5-chloroxine; Lekosept; Domeform; Clioquinol; Amebil; Alchloquin; Amoenol; Bactol; Barquinol; Budoform; Chinoform; Eczecidin; Enteroquinol; Entero-Septol; Entero-Vioform; Enterozol; Entrokin; Hi-Enterol; Iodochlorhydroxyquin; Iodochloroxyquinoline; Iodoenterol; Nioform; Quinambicide; Rometin; Quinoform; Vioform; Iodochlorohydroxyquinol; Iodochlorohydroxyquinoline; Chloroiodoquine; 7-Iodo-5-chloro-8-hydroxyquinoline; Cliquinol; Emaform; Entero-bio form; Enterum locorten; Hydriodide-enterol; Iodenterol; Vioform n.n.r.; [ChemFinder]
Category
Pharmaceuticals
Sources/Uses
Used as a medicinal cream, ointment, or powder; [HSDB]
Comments
Allergic contact dermatitis reported in patients using this antibiotic topically; [Marks, p. 123-4] An epidemic of subacute myelo-optico-neuropathy occurred in Japan from 1956 until 1970. Approximately 10,000 cases were reported with visual impairment, lower extremity paresthesias and weakness, and other symptoms. Symptoms resolved after the oral medication was discontinued. Neurotoxicity developed in patients who received total doses greater that 750 mg/day for four weeks. [HSDB]
Biomedical References

Adverse Effects

Skin Sensitizer
Yes

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: