Chlorpromazine

Agent Name
Chlorpromazine
CAS Number
50-53-3
Formula
C17-H19-Cl-N2-S
Major Category
Other Uses
Synonyms
2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine; Chloropromazine; Ormazine; Thor-prom; Thorazine; Largactil; [ChemFinder]
Category
Pharmaceuticals
Comments
Allergic and photoallergic contact dermatitis reported in pharmaceutical, healthcare, and animal care workers; [Kanerva, p. 1138] As an oral medication, chlorpromazine is used to treat schizophrenia. Many side effects have been reported after ingestion of therapeutic doses, including drug-induced hepatitis. [HSDB] Chlorpromazine may induce photosensitivity in patients taking chlorpromazine systemically (photodrug reaction). [Marks, p. 201-3] Danger of photo-contact dermatitis; [MAK]
Biomedical References

Exposure Assessment

Explanatory Notes
"Danger of sensitization of skin." [MAK]

Adverse Effects

Skin Sensitizer
Yes
Dermatotoxin
PACD (photoallergic contact dermatitis)

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: