Dansyl chloride
Agent Name
Dansyl chloride
CAS Number
605-65-2
Formula
C12-H12-Cl-N-O2-S
Major Category
Other Classes
Synonyms
1-Chlorosulfonyl-5-dimethylaminonaphthalene; 1-Dimethylaminonaphthalene-5-sulfonyl chloride; 5-Dimethylaminonaphthalene-1-sulfonyl chloride; DNS chloride; Dansyl; Dimethylaminonaphthalenesulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-; 5-Dimethylaminonaphthalene-1-sulphonyl chloride; [ChemIDplus] 5-(Dimethylamino)-1-naphthalenesulfonyl chloride; [Merck Index] 1-(Dimethylamino)-5-naphthalenesulfonyl chloride; [RTECS] UN3261
Category
Naphthalenes
Description
Yellow-orange solid; [Merck Index] Orange powder; [Alfa Aesar MSDS]
Sources/Uses
Used in fluorescent labeling and high performance liquid chromatography (HPLC); [Merck Index] "Dansyl chloride is widely used to modify amino acids; specifically, protein sequencing and amino acid analysis." [Wikipedia]
Comments
Intravenous LD50 (mouse) = 56 mg/kg; [RTECS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS]
Biomedical References
Exposure Assessment
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Corrosive solid, organic, n.o.s."
Adverse Effects
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.