1,2-Dimethylhydrazine

Synonyms

1,2-DMH; 1,2-Dimethyl-hydrazine; 1,2-Dimethylhydrazin [German]; DMH; Hydrazine, 1,2-dimethyl-; Hydrazomethane; N,N'-Dimethylhydrazine; SDMH; Symetryczna dwumetylohydrazyna; Symetryczna dwumetylohydrazyna [Polish]; Symmetrical-dimethylhydrazine; sym-Dimethylhydrazine; Dimethylhydrazine, symmetrical; [ChemIDplus] UN2382

Category

Hydrazines

Description

Colorless liquid with a fishy or ammonia-like odor; [NIOSH] Hygroscopic liquid; Fumes and gradually turns yellow in air; [Merck Index]

Sources/Uses

Used in research and not used commercially; [HSDB] Used in the production of photographic chemicals; [CAMEO]

Comments

Liquid causes second or third degree burns after short contact; [CHRIS] Patients poisoned by hydrazines may develop methemoglobinemia and liver injury; Emergency treatment: "Hydrazines"; [HSDB] Inhalation of hydrazine compounds in high concentrations can induce seizures and coma; Corrosive to skin; [Merck Index] Toxic after absorption through skin; Inhalation of high concentrations can induce pulmonary irritation and edema; [CAMEO] A strong reducing agent; An eye and respiratory tract irritant; May injure liver; Can be absorbed through skin; The kidney is target organ in experimental animals; [ICSC] Danger of skin sensitization; [MAK] Causes convulsions and dyspnea in lethal-dose inhalation studies of rats; [RTECS]

Biomedical References

Yes

69.9 mm Hg

LC50 (rat) = 280 ppm/4hr

Explanatory Notes

Highly flammable; Flash point = 5 deg F; [CAMEO] VP from HSDB;

Reference Link #2

Yes

Yes

MetHgb is secondary toxic effect

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Skin burns

Probable (2a)

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Encephalopathy, acute toxic
• Pneumonitis, toxic