Agent Name
Alternative Name
CAS Number
Major Category
Nitrogen Compounds
5-Nitro-2-toluidine formula graphical representation
Nitro-o-toluidine; AI3-01557; Amarthol Fast Scarlet G Base; Amarthol Fast Scarlet G Salt; 2-Amino-4-nitrotoluene; Azoene Fast Scarlet GC Base; Azoene Fast Scarlet GC Salt; Azofix Scarlet G Salt; Azogene Fast Scarlet G; Benzenamine, 2-methyl-5-nitro-; CI Azoic Diazo Component 12; CI 37105; Dainichi Fast Scarlet G Base; Daito Scarlet Base G; Devol Scarlet B; Devol Scarlet G Salt; Diabase Scarlet G; Diazo Fast Scarlet G; Fast Red SG Base; Fast Scarlet G; Fast Scarlet G Base; Fast Scarlet Base J; Fast Scarlet T Base; Fast Scarlet M4NT Base; Fast Scarlet GC Base; Fast Scarlet G Salt; Fast Scarlet J Salt; Hiltonil Fast Scarlet G Base; Hiltonil Fast Scarlet GC Base; Hiltonil Fast Scarlet G Salt; Kayaku Scarlet G Base; Lake Scarlet G Base; Lithosol Orange R Base; 2-Methyl-5-nitroaniline; 6-Methyl-3-nitroaniline; 2-Methyl-5-nitro-benzenamine; Mitsui Scarlet G Base; Naphthanil Scarlet G Base; Naphtoelan Fast Scarlet G Base; Naphtoelan Fast Scarlet G Salt; 4-Nitro-2-aminotoluene; 3-Nitro-6-methylaniline; PNOT; Scarlet G Base; Scarlet Base Ciba II; Scarlet Base IRGA II; Scarlet Base NSP Sugai Fast Scarlet G Base; Symulon Scarlet G Base; o-Toluidine, 5-nitro-; Nitro-o-toluidine; [HSDB] 4-Nitro-2-aminotoluene; [Guide to Occupational Exposure Values, 2002] UN2660
Yellow crystals; [ACGIH]
Workers are exposed during production or handling of more than 35 commercial dyes (orange or red) of which 5-nitro-o-toluidine is the major component; [ACGIH]
Several Japanese workers were admitted to the hospital with severe liver damage after handling repeatedly (12-20 times) 5-nitro-o-toluidine for 4-5 hours at a time. Workers had scooped the powder by hand while wearing respirators. [Gut 2002 Feb;50(2):266-70] Methemoglobinemia is a potential adverse effect after exposure to this agent. [HSDB]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
1 mg/m3, inhalable fraction and vapor
Vapor Pressure
0.000975 mm Hg
Explanatory Notes
VP from HSDB;

Adverse Effects

MetHgb is secondary toxic effect
Occupational hepatotoxin (principal effect)
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Confirmed Animal

Diseases, Processes, and Activities Linked to This Agent


Occupational diseases associated with exposure to this agent: