N-Vinyl-2-pyrrolidone
Agent Name
N-Vinyl-2-pyrrolidone
Alternative Name
N-Vinyl-2-pyrrolidinone
CAS Number
88-12-0
Formula
C6-H9-N-O
Major Category
Plastics & Rubber
Synonyms
1-Vinyl-2-pyrrolidinone; 1-Vinyl-2-pyrrolidinone, monomer; 1-Vinyl-2-pyrrolidone; 1-Vinylpyrrolidinone; 1-Vinylpyrrolidone; N-Vinyl-2-pyrrolidinone; N-Vinyl-2-pyrrolidone; N-Vinylpyrrolidinone; N-Vinylpyrrolidone; V-Pyrol; Vinyl-2-pyrrolidone; Vinylbutyrolactam; Vinylpyrrolidinone; Vinylpyrrolidone; [ChemIDplus]
Category
Other Monomers
Description
Clear to light straw colored liquid; [HSDB]
Sources/Uses
Used as a monomer in the production of polyvinyl pyrrolidone; also used in the production of other polymers and organic chemicals; [ACGIH]
Comments
No health effects found in a study of 94 production workers; Animal studies show evidence of liver damage in acute and chronic studies; [ACGIH] An eye and respiratory tract irritant; May cause liver injury; [ICSC] See "N-Methyl-2-pyrrolidone."
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
No
TLV (ACGIH)
0.05 ppm
MAK
0.01 ppm
Vapor Pressure
0.1 mm Hg
Lethal Concentration
LC50 (rat) = 3,200 mg/m3/4h
Explanatory Notes
Flash point = 95 deg C; VP from ACGIH (2003);
NFPA
must be preheated
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Confirmed Animal
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: