Agent Name
Dextran sulfate
Major Category
Biological Agents
Synonyms
Dextran polysulfate; Dextran sulfate 500; Dextran sulfuric acid; Dextran sulfuric acid ester; Dextran sulphate; PF 51; Polydextran sulfate; Dextran, hydrogen sulfate; [ChemIDplus]
Sources/Uses
"Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications." [ChemIDplus]
Comments
Intraperitoneal LD50 (mouse) = 341 mg/kg; [RTECS] See "Dextran."
Other Information
No other related information on this agent was found.