Benzoyl chloride

Agent Name
Benzoyl chloride
Alternative Name
Benzoic acid chloride
CAS Number
98-88-4
Formula
C7-H5-Cl-O
Major Category
Toxic Gases & Vapors
Benzoyl chloride formula graphical representation
Synonyms
Benzoic acid chloride; Benzaldehyde, alpha-chloro-; Benzenecarbonyl chloride; Benzoic acid, chloride; alpha-Chlorobenzaldehyde; [ChemIDplus] UN1736
Category
Acid Halides
Description
Colorless, fuming liquid with a pungent odor; [HSDB] Colorless to slightly brown liquid; [CHRIS]
Sources/Uses
Used in chemical production; [HSDB]
Comments
Corrosive to skin; [Quick CPC] A lachrymator; High inhalation exposure can cause pulmonary edema; [HSDB] A corrosive substance that can cause pulmonary edema; [ICSC] In lethal concentration studies, rats had labored breathing and histological evidence of emphysema; Hydrolyzes to produce corrosive HCl in biological systems, and this is the mechanism of toxicity; Danger of dermal sensitization; [AIHA] Slowly reacts with water forming hydrochloric acid (reacts more rapidly with steam); Short-term exposure causes second- and third-degree skin burns and severe eye injury; Vapors cause severe eye and throat irritation (and possibly eye and lung injury) and are intolerable even at low concentrations; [CHRIS] Human inhalation of 2 ppm for 1 minute causes other changes in olfaction and lungs, thorax, or respiration; [RTECS] Causes burns; A lachrymator; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; May cause skin sensitization; Harmful by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
Ceiling (ACGIH)
0.5 ppm
Vapor Pressure
0.7 mm Hg
Lethal Concentration
LC50 (rat) = 1,870 mg/m3/2hr
Explanatory Notes
Flash point = 68 deg C; VP from HSDB;
NFPA
high ambient temp required
ERPG-1
0.3 ppm
ERPG-2
5 ppm
ERPG-3
20 ppm
WEEL
Ceiling = 5 ppm

Adverse Effects

Lachrymator
Yes
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
IARC Carcinogen
Probable (2a)
ACGIH Carcinogen
Not Classifiable

Diseases, Processes, and Activities Linked to This Agent

Other Information
No other related information on this agent was found.