Agent Name
Chloroacetic acid
Alternative Name
Monochloroacetic acid
Major Category
Other Classes
Synonyms
Monochloroacetic acid; Acetic acid, chloro-; Acide chloracetique [French]; Acide chloracetique [ISO-French]; Acide chloroacetique [French]; Acide monochloracetique [French]; Acidomonocloroacetico [Italian]; Chloracetic acid; Chloroacetic acid; Chloroethanoic acid; Kyselina chloroctova [Czech]; MCA; Monochloorazijnzuur [Dutch]; Monochloracetic acid; Monochloressigsaeure [German]; Monochloroacetic acid; Monochloroethanoic acid; Acetic acid, 2-chloro-; Acetic acid, chloro-; [ChemIDplus] MCA; [AIHA] UN1750; UN1751; UN3250;
Description
Colorless, white, or light-brown crystals with a vinegar-like odor; [HSDB]
Sources/Uses
Used as a herbicide, preservative, bacteriostat, and chemical intermediate; [HSDB]
Comments
Corrosive to skin; [Quick CPC] Inhalation of aerosol can cause lung edema; May be toxic to the heart, kidneys, and CNS; [ICSC] A severe skin, eye, and respiratory tract irritant; Liquid can burn skin and eyes; [CAMEO] Several accidents have been described; Molten MCA causes severe burns; it is absorbed through the skin; Signs of poisoning include metabolic acidosis, cardiac arrhythmias, disorientation, coma, rhabdomyolysis, renal failure, and cerebral edema; [AIHA]
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.5 ppm, inhalable fraction and vapor
Vapor Pressure
0.065 mm Hg
Odor Threshold Low
0.045 ppm
Odor Threshold High
6.14 ppm
Lethal Concentration
LC50 (rat) = 180 mg/m3
Explanatory Notes
Melting point = 50-63 degrees C; [HSDB] Odor threshold from CHEMINFO; Flash point = 126 deg C; VP from HSDB;
Neurotoxin
Other CNS neurotoxin
ACGIH Carcinogen
Not Classifiable
Processes
Industrial Processes with risk of exposure: