Dithioerythritol
Agent Name
Dithioerythritol
CAS Number
6892-68-8
Formula
C4-H10-O2-S2
Major Category
Biological Agents
Synonyms
(R*,S*)-1,4-Dimercapto-2,3-butanediol; 1,4-Dithioerythritol; DTE; (R*,S*)-1,4-Dimercaptobutane-2,3-diol; 2,3-Butanediol, 1,4-dimercapto-, (2R,3S)-rel-; 2,3-Butanediol, 1,4-dimercapto-, (R*,S*)- (9CI); 2,3-Butanediol, 1,4-dimercapto-, (theta,S)-; Erythritol, 1,4-dithio-; [ChemIDplus] Cleland’s reagent; Erythro-2,3-Dihydroxy-1,4-butanedithiol; Erythro-1,4-Dimercapto-2,3-butanediol; [Sigma-Aldrich MSDS]
Category
Monosaccharides and Derivatives
Description
White powder; [Sigma-Aldrich MSDS]
Sources/Uses
Used as a reagent to prevent oxidation of sulfhydryl groups and to reduce disulfides to sulfhydryl groups; [ChemIDplus] "Dithioerythritol (DTE) is a sulfur containing sugar derived from the corresponding 4-carbon monosaccharide erythrose." [Wikipedia]
Comments
Causes convulsions in intramuscular lethal-dose studies of mice (LD50 = 309 mg/kg); [RTECS] A skin and strong eye irritant; May cause CNS depression; [Sigma-Aldrich MSDS]
Biomedical References
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.