Trifluoromethanesulfonic acid
Agent Name
Trifluoromethanesulfonic acid
Major Category
Other Classes
Synonyms
Methanesulfonic acid, trifluoro-; Perfluoromethanesulfonic acid; Methanesulfonic acid, 1,1,1-trifluoro-; [ChemIDplus] Triflic acid; TFMSA; [Merck Index] UN3265
Description
Colorless hygroscopic liquid; [Merck Index]
Sources/Uses
Used as a catalyst, solvent for ESR, acid titrant, and with trifluoroacetic acid in peptide synthesis; [Merck Index]
Comments
Highly corrosive to skin; [Quick CPC] "One of the strongest acids known." May cause burns; [Merck Index] Oral LD50 (rat) is between 500 and 2,000 mg/kg; An acute dermal toxicity study of rats at 2,000 mg/kg produced extensive and severe local skin effects considered to be life threatening; 50 mg/kg doses were tolerated and showed no significant adverse effects at necropsy; No evidence of skin sensitization in guinea pigs; No evidence of mutagenicity; [EPA TSCA] Causes burns; Inhalation of high concentration can cause chemical pneumonitis; [Alfa Aesar MSDS]
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Corrosive liquid, acidic, organic, n.o.s."
Other Information
No other related information on this agent was found.