Methyl propyl ketone

Agent Name
Methyl propyl ketone
Alternative Name
2-Pentanone
CAS Number
107-87-9
Formula
C5-H10-O
Major Category
Solvents
Methyl propyl ketone formula graphical representation
Synonyms
2-Pentanone (natural); Ethyl acetone; Ethylacetone; Methyl n-propyl ketone; Methyl propyl ketone; Methyl-propyl-cetone [French]; Methylpropyl ketone; Metylopropyloketon [Polish]; Propyl methyl ketone; MPK; [ChemIDplus] UN1249
Category
Ketones (<C12)
Description
Colorless to water-white liquid with a characteristic acetone-like odor; [NIOSH]
Sources/Uses
Used as a solvent, a flavoring agent, and in organic synthesis; [ACGIH] Used as a solvent for lacquers and surface coatings; [HSDB]
Comments
Causes CNS depression and fatty degeneration of the liver after inhalation of high doses by experimental animals; A respiratory tract irritant; [ACGIH]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
STEL (ACGIH)
150 ppm
PEL (OSHA)
200 ppm
IDLH (NIOSH)
1500 ppm
Excerpts from Documentation for IDLHs
Exposure to a concentration of 1,500 ppm was associated with complaints of ocular and upper respiratory irritation [Yant et al. 1936].
Vapor Pressure
35.4 mm Hg
Odor Threshold Low
3.1 ppm
Odor Threshold High
13.6 ppm
RD50
12832 ppm
Lethal Concentration
LCLo (rat) = 2,000 ppm/4H
Explanatory Notes
Detection odor threshold from AIHA (mean = 7.7 ppm); Flash point equals 7 deg C; [ACGIH] VP from HSDB;
NFPA
may ignite at ambient temp

Adverse Effects

Neurotoxin
Acute solvent syndrome

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: