2,4-Pentanedione
Agent Name
2,4-Pentanedione
Alternative Name
Acetyl acetone
CAS Number
123-54-6
Formula
C5-H8-O2
Major Category
Other Classes
Synonyms
Acetyl acetone; 2,4-Dioxopentane; 2-Propanone, acetyl-; ACAC; Acetoacetone; Acetone, acetyl-; Acetyl 2-propanone; Acetylacetone; Diacetylmethane; Pentan-2,4-dione; Pentanedione; Pentanedione-2,4; UN2310; [ChemIDplus]
Category
Aliphatic Ketones, Other
Description
Colorless to yellow liquid with a pleasant odor; [CHEMINFO MSDS] Rancid odor at room temperature; [ACGIH]
Sources/Uses
Used as a chemical intermediate, solvent, metal chelating agent, lubricant additive, and pesticide; [Hawley] Used as a metal chelator, lubricant additive, corrosion inhibitor, polyolefin modifier, and intermediate; [ACGIH]
Comments
Causes narcosis with an oral LD50 of 575-1000 mg/kg in rats; Rats inhaling 650 ppm six hours five times weekly for 14 weeks show degenerative changes of the brain and thymus; No neurotoxicity at 307 ppm; [ACGIH] Inhalation of high concentrations causes narcosis; [CHEMINFO MSDS]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
25 ppm
MAK
20 ppm
Vapor Pressure
2.96 mm Hg
Lethal Concentration
LCLo (rat) = 1,000 ppm/4H
Explanatory Notes
VP from HSDB;
Half Life
About 10.75 hours in rats; [ACGIH]
NFPA
may ignite at ambient temp
Adverse Effects
Neurotoxin
Acute solvent syndrome
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: