Methyl propyl ketone

Synonyms

2-Pentanone (natural); Ethyl acetone; Ethylacetone; Methyl n-propyl ketone; Methyl propyl ketone; Methyl-propyl-cetone [French]; Methylpropyl ketone; Metylopropyloketon [Polish]; Propyl methyl ketone; MPK; [ChemIDplus] UN1249

Category

Ketones (<C12)

Description

Colorless to water-white liquid with a characteristic acetone-like odor; [NIOSH]

Sources/Uses

Used as a solvent, a flavoring agent, and in organic synthesis; [ACGIH] Used as a solvent for lacquers and surface coatings; [HSDB]

Comments

Causes CNS depression and fatty degeneration of the liver after inhalation of high doses by experimental animals; A respiratory tract irritant; [ACGIH]

Biomedical References

Insufficient data

150 ppm

200 ppm

1500 ppm

Excerpts from Documentation for IDLHs

Exposure to a concentration of 1,500 ppm was associated with complaints of ocular and upper respiratory irritation [Yant et al. 1936].

35.4 mm Hg

3.1 ppm

Odor Threshold High

13.6 ppm

12832 ppm

LCLo (rat) = 2,000 ppm/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 7.7 ppm); Flash point equals 7 deg C; [ACGIH] VP from HSDB;

may ignite at ambient temp

Acute solvent syndrome

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Painting (Solvents)