Terpinolene

Synonyms

1,4(8)-Terpadiene; 1,4(8)-p-Menthadiene; 1-Methyl-4-(1-methylethylidene)cyclohexene; 1-Methyl-4-isopropylidene-1-cyclohexene; 4-Isopropylidene-1-methylcyclohexene; Cyclohexene, 1-methyl-4-(1-methylethylidene)-; Isoterpinene; Nofmer TP; Tereben; Terpinolen; p-Menth-1,4(8)-diene; p-Mentha-1,4(8)-diene; Cyclohexene, 3-methyl-6-(1-methylethylidene)- (9CI); UN2541; [ChemIDplus]

Category

Terpenes

Description

Colorless to pale-yellow, oily liquid with a pine-like odor; [HSDB]

Sources/Uses

Used as a fragrance and food flavoring agent; Used as a solvent for resins and oils and a chemical intermediate; [HSDB]

Comments

Safe when used as a flavoring agent; [JECFA] Not a sensitizer in the maximization test; A positive patch test was reported in a woman using a machine cleaner containing terpinolene. [NTP] Included in list of "established contact allergens in humans"; [EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)] See "3-Carene" and "Limonene."

Biomedical References

0.743 mm Hg

Explanatory Notes

VP from ChemIDplus;

Yes

Acute solvent syndrome

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Solvents, acute toxic effect