1,3-Dioxolane

Synonyms

1,3-Dioxacyclopentane; 1,3-Dioxolan; 1,3-Dioxole, dihydro-; Dioxolan [Czech]; Dioxolane; Ethylene glycol formal; Formal glycol; Glycol formal; Glycol methylene ether; Glycolformal; [ChemIDplus]

Category

Ethers (<C12)

Description

Colorless liquid with a mild, ethereal odor; [ACGIH]

Sources/Uses

Used as a solvent and extractant for fats, waxes, and dyes; Used in the production of phenolic-novolak resins; [HSDB] Used as a monomer to produce polyacetals and a solvent for polyesters, vinyls, and epoxys; May be used as a paint stripper; [ACGIH]

Comments

In animal studies, 1,3-dioxolane is a CNS depressant and has some effects on the liver; [HSDB] A skin irritant and severe eye irritant; Blood (leukopenia) and reproductive changes occur in animal studies. [ACGIH]

Biomedical References

No

20 ppm

50 ppm

79 mm Hg

LC50 (rat) = 20,650 mg/m3/4H

Explanatory Notes

VP from ChemIDplus;

may ignite at ambient temp

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Painting (Solvents)
• Plastic Composites Manufacturing