N-Butylbenzenesulfonamide

Synonyms

BM 4 (sulfonamide); Benzenesulfonic acid butyl amide; Cetamoll BMB; Dellatol BBS; N-Butylbenzene sulfonamide; Plasthall BSA; Plastomoll BMB; Uniplex 214; Benzenesulfonamide, N-butyl-; N-Butylbenzenesulphonamide; [ChemIDplus] BBSA; n-Butylamide of benzenesulphonic acid; N-Butylbenzolsulfonsaureamid; N-Butylsulfonamid; [IUCLID] N-n-Butylbenzenesulfonamide; N-n-Butylamide of benzenesulphonic acid; [EPA ChAMP: Submission]

Category

Sulfonamides

Description

Colorless oily liquid with nearly no odor; [EPA ChAMP: Submission]

Sources/Uses

Used in the polymers and textile processing industries; Used as a plasticizer, smelting agent for moulding, and softener; [IUCLID] Used mainly as a plasticizer; [EPA ChAMP: Submission]

Comments

Not an eye irritant in guinea pigs; Causes mild eye irritation in rabbits (classified by the EC as irritating); [IUCLID] A 28-day oral study of rats produced 100% mortality at the highest tested dose (1,000 mg/kg/day); Low frequency and severity of nerve fiber degeneration in the spinal cord and sciatic nerves, liver enlargement, hepatocyte hypertrophy, thymic atrophy at 150 mg/kg/day; No changes in functional performance observations, body weight/food consumption, or altered clinical biochemistry at 50 and 150 mg/kg/day (NOAEL of 50 mg/kg/day); [EPA ChAMP: Submission] Human inhalation of 3.7 mg/m3 causes conjunctive irritation and structural or functional changes in trachea or bronchi; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS]

Biomedical References

LCLo (rat) = 385 mg/m3/4hr

Explanatory Notes

LC50 (rat) > 4,066 mg/m3/4hr

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Processes

Industrial Processes with risk of exposure:

• Textiles (Fiber & Fabric Manufacturing)