Agent Name
N-Ethylmaleimide
Major Category
Other Uses
Synonyms
Ethylmaleimide; Maleic acid N-ethylimide; Maleimide, N-ethyl-; NEM; 1H-Pyrrole-2,5-dione, 1-ethyl-; [ChemIDplus] 1-Ethyl-1H-pyrrole-2,5-dione; [Merck Index] UN2928
Category
Biochemical Research
Description
Solid; [Merck Index] Colorless crystals; [Sigma-Aldrich MSDS]
Sources/Uses
Used in cancer research; [Merck Index] "A sulfhydryl reagent that is widely used in experimental biochemical studies." [ChemIDplus]
Comments
Causes somnolence and convulsions in oral lethal-dose studies of rats; [RTECS] A strong irritant; A lachrymator when liquid; [Merck Index] Causes burns; May cause skin sensitization; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Highly toxic by ingestion; Toxic by skin absorption; [Sigma-Aldrich MSDS] Search for 128-53-0 AND (sensitizer OR sensitization OR allergic): no results; [PubMed]
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Toxic solid, corrosive, organic, n.o.s."
Other Information
No other related information on this agent was found.