Diketene
Agent Name
Diketene
CAS Number
674-82-8
Formula
C4-H4-O2
Major Category
Toxic Gases & Vapors
Synonyms
2-Oxetanone, 4-methylene-; 3-Buteno-beta-lactone; 3-Butenoic acid, 3-hydroxy-, beta-lactone; 4-Methylene-2-oxetanone; Ethenone, dimer; Ethenone, dimer (VAN); Ketene, dimer; Vinylaceto-beta-lactone; But-3-en-3-olide; [ChemIDplus]
Category
Other Toxic Gases & Vapors
Description
Colorless liquid with a disagreeable odor; [CAMEO]
Sources/Uses
Used to manufacture paints and pharmaceuticals; [CAMEO]
Comments
A skin and eye irritant; [CAMEO] Inhalation may cause acute pulmonary edema; [ICSC] Diketene, stabilized (UN2521) has warning of explosive polymerization; [ERG 2016] A severe lachrymator--see "Ketene" in CAMEO;
Biomedical References
Exposure Assessment
TIH
Yes
Vapor Pressure
10.7 mm Hg
Lethal Concentration
LCLo (rat) = 20,000 ppm/1H
Explosive Polymerization
Yes
Explanatory Notes
Flash point = 90 degrees F; [CAMEO] The Guide from the Emergency Response Guidebook is for "Diketene, inhibited." VP from ChemIDplus;
NFPA
may ignite at ambient temp
ERPG-1
1 ppm
ERPG-2
5 ppm
ERPG-3
20 ppm
Adverse Effects
Lachrymator
Yes
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: