Rhodamine 123
Agent Name
Rhodamine 123
CAS Number
62669-70-9
Formula
C21-H17-N2-O3.Cl
Major Category
Dyes
Synonyms
2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester monohydrochloride; 3,6-Diamino-9-(2-(methoxycarbonyl)phenyl)xanthylium chloride; Benzoic acid, 2-(6-amino-3-imino-3H-xanthen-9-yl)-, methyl ester, monohydrochloride; RH 123; Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride; [ChemIDplus]
Category
Rhodamine Dyes
Description
Red to brown powder; [Acros Organics MSDS]
Sources/Uses
"A fluorescent probe with low toxicity which is a potent substrate for P-glycoprotein and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of P-glycoprotein in both normal and malignant cells. (Leukemia 1997;11(7):1124-30)" [ChemIDplus]
Comments
May cause irritation; Reports of adverse reproductive effects in experimental animals; [Acros Organics MSDS]
Biomedical References
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.