tert-Amyl methyl ether
Agent Name
tert-Amyl methyl ether
Alternative Name
TAME
CAS Number
994-05-8
Formula
C6-H14-O
Major Category
Solvents
Synonyms
TAME; 1,1-Dimethylpropyl methyl ether; 2-Methoxy-2-methylbutane; 2-Methyl-2-methoxybutane; Methyl 1,1-dimethylpropyl ether; Methyl tert-amyl ether; Methyl tert-pentyl ether; TAME (ether); Tertiary amyl methyl ether; tert-Pentyl methyl ether; tertiary-Amyl methyl ether; [ChemIDplus]
Category
Ethers (<C12)
Sources/Uses
Used as a gasoline additive to reduce emissions; [ACGIH]
Comments
Toxicity in animal studies includes CNS depression and increased liver weights; TAME is embryotoxic in high-dose studies of pregnant mice and rats; [ACGIH]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
20 ppm
Vapor Pressure
75.2 mm Hg
Odor Threshold Low
0.027 ppm
Lethal Concentration
LC50 (rat) = >5,400 mg/m3/4H
Explanatory Notes
Detection odor threshold from ACGIH; VP from ChemIDplus;
Adverse Effects
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Reproductive Toxin
Yes
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: