Polychlorinated terphenyls
Agent Name
Polychlorinated terphenyls
Major Category
Other Classes
Synonyms
Polychlorinated terphenyl; Terphenyl, chlorinated; [ChemIDplus] PCTs; PCT; Aroclor (series 54); Electrophenyl T-60; Clophen Harz (W); Cloresil (A,B,100); Leromoll; [Reference #1]
Category
Halogenated Polyaromatics
Description
Yellow resins; [Reference #1]
Sources/Uses
Used as waxes for metal parts, fire retardants, in plasticizer applications, hydraulic fluids, and lubricants (PCB substitute); [Reference #1]
Comments
Causes liver changes in oral lethal-dose studies of mice; Causes changes in liver weight, changes in blood serum composition, and effects on transaminases in 30-week constant oral studies of rats; [RTECS] The liver is the main target organ for short-term toxicity in experimental animals; Effects to skin and eyes (acne-form lesions), body weight loss, and NOEL's between 20 and 250 mg/kg have also been demonstrated; Chronic exposure in mice has produced hepatocellular carcinomas; [Reference #1] See "p-Terphenyl." See "Polychlorinated biphenyls."
Restricted
Banned in Canada and the USA for all commercial, manufacturing, and processing uses; Banned in the EEC for all uses except products containing less than 0.01% PCT by weight; [Reference #1]
Explanatory Notes
For correct structure, see Polychlorinated terphenyls in Wikipedia.
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases
Occupational diseases associated with exposure to this agent: