Antimony trioxide

Agent Name
Antimony trioxide
CAS Number
1309-64-4
Formula
O3-Sb2
Major Category
Metals
Synonyms
Antimonious oxide; Antimony Bloom 100A; Antimony Bloom 500A; Antimony White; Antimony oxide (SB203); Antimony oxide (Sb2O3); Antimony sesquioxide; Antimony trioxide; Antimony trioxide production; Antimony(3+) oxide; Antox; Atox B; Atox F; Atox R; Atox S; C.I. 77052; C.I. Pigment White 11; CI 77052; CI Pigment white 11; Chemetron fire shield; Dechlorane A-O; Diantimony trioxide; Exitelite; FireShield H; FireShield LS-FR; Fireshield FSPO 405; Flame Cut 610; Flame Cut 610R; Flameguard VF 59; Flowers of antimony; Microfine A 05; Nyacol A 1510LP; Nyacol A 1530; Octoguard FR 10; Patox C; Patox H; Patox L; Patox M; Patox S; Senarmontite; Stibiox MS; Thermoguard B; Thermoguard L; Thermoguard S; Timonox; Timonox White Star; Twinkling star; Valentinite; Weisspiessglanz; Weisspiessglanz [German]; White star; [ChemIDplus]
Category
Metalloid Compounds (Antimony)
Description
Crystals; [Merck Index]
Sources/Uses
Used to make tartar emetic, paint pigments, stains for iron and copper, enamels, ceramics, glasses, mordants, plastic stabilizers, phosphors, and flame-retardants for canvas, textiles, and plastics; [HSDB] Workers may be exposed manufacturing or using batteries, printing machines, bearings, textiles, and ceramics; [Kanerva, p. 1753]
Comments
The TLV Basis is pneumonitis. "Human studies have focused on possible lung carcinogenicity, but have been inconclusive, in part because of common workplace co-exposure with arsenic, a known human lung carcinogen." Several studies show the association of occupational antimony trioxide exposure with "benign pneumoconiosis." [ACGIH] Smelter workers exposed to antimony trioxide complained of rhinitis, pharyngitis, gastroenteritis, and bronchitis. Cases of septal perforation were reported. [IARC] Antimony trioxide caused allergic contact dermatitis in two ceramics workers. [Kanerva, p. 1753] Antimony is a "hepatotoxic agent." [Zimmerman, p. 4] See "Antimony" and linked occupational diseases.
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
No
TLV (ACGIH)
0.02 mg/m3, inhalable particulate matter
PEL (OSHA)
0.5 mg/m3, as Sb
IDLH (NIOSH)
50 mg/m3, as Sb
NFPA
will not burn

Adverse Effects

Skin Sensitizer
Yes
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Possible (2b)
NTP Carcinogen
Anticipated human carcinogen
ACGIH Carcinogen
Suspected Human

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes
Activities

Activities with risk of exposure: