Ro 15-4513
Agent Name
Ro 15-4513
CAS Number
91917-65-6
Formula
C15-H14-N6-O3
Major Category
Other Uses
Synonyms
Ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo-1,4-benzodiazepine-3-carboxylate; RO-154513; Ro 154513; Ro15-4513; 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-azido-5,6-dihydro-5-methyl-6-oxo-, ethyl ester; [ChemIDplus]
Category
Biochemical Research
Description
White or beige solid; [Sigma-Aldrich MSDS]
Sources/Uses
"Ro15-4513 is a weak partial inverse agonist of the benzodiazepine class of drugs, developed by Hoffmann–La Roche in the 1980s. It is structurally related to the benzodiazepine antidote flumazenil. . . . Labelling Ro15-4513 with carbon-11 leads to the possibility of its use in PET imaging of the brain." [Wikipedia] "A partial inverse agonist of benzodiazepine receptors." [ChemIDplus]
Comments
May cause irritation; [Sigma-Aldrich MSDS]
Biomedical References
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.