Selenomethionine
Agent Name
Selenomethionine
CAS Number
1464-42-2
Formula
C5-H11-N-O2-Se
Major Category
Biological Agents
Synonyms
2-Amino-4-(methylselenyl)butyric acid; Butanoic acid, 2-amino-4-(methylseleno)-; Butyric acid, 2-amino-4-(methylselenyl)-; Methionine, seleno; Selenium methionine; [ChemIDplus] UN3283
Category
Amino Acids and Derivatives
Description
DL- and L-forms are solids; [Merck Index] White crystalline solid; [Sigma-Aldrich MSDS]
Sources/Uses
An analog of methionine containing selenium; [Merck Index] Used as a medication and dietary supplement; [HSDB] "Selenomethionine is a naturally occurring amino acid containing selenium." [Wikipedia] "Methionine containing selenium in place of sulfur." [mediLexicon]
Comments
Causes flaccid paralysis without anesthesia in intravenous lethal-dose studies of mice (LD50 = 22 mg/kg); Causes changes in motor activity and effects on porphyrin in 3-day intermittent intraperitoneal studies of rats; Causes paternal reproductive effects in 28-week intermittent oral studies of dogs; Causes changes in spleen and decreased cellular immune response in 50-day constant oral studies of mice; [RTECS] May cause irritation; Toxic by ingestion and inhalation; Prolonged or repeated exposure may cause organ injury; Targets the eyes, liver, kidney, blood, endocrine system, and nerves; [Sigma-Aldrich MSDS] "See Methionine."
Biomedical References
Exposure Assessment
Vapor Pressure
7.5E-08 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Selenium compound, solid, n.o.s."
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.