Allethrin

Synonyms

2-Methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate trans-(+)-; DL-2-Allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one, d-trans-chrysanthemum monocarboxylic ester; d-trans-Allethrin; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl ester, trans-(+)-; d-trans-Chrysanthemic acid of d-allethrone; [ChemIDplus] Trade names include Alleviate, Pynamin, d-Allethrin, d-cisAllethrin, Bioallethrin, Esbiothrin, Pyresin, Pyrexcel, Pyrocide, and trans-Allethrin. [EXTOXNET]

Category

Pyrethrins/Pyrethroids

Description

Yellow liquid with a mild aromatic odor; [EXTOXNET]

Sources/Uses

Used in homes and gardens to kill flies and mosquitoes; The d-trans isomer is a more potent insecticide used to control animal parasites. Sold as mosquito coils, mats, oil formulations, and sprays; [EXTOXNET]

Comments

Slightly toxic after skin absorption or ingestion with an oral LD50 of 1100 mg/kg in male rats; Liver injury is detected in animal experiments with high oral doses. [EXTOXNET] See Bioallethrin, RN: 584-79-2, with LCLo (rats) = 13,800 mg/m3/4H and a vapor pressure = 0.0000012 mm Hg. [ChemIDplus] Pyrethroids have low toxicity to humans after dermal exposure. Of 573 dermal or ingestion poisoning cases in China, 51 patients had disturbed consciousness and 34 had seizures. Of those, only five were occupationally exposed. Seizures are more commonly related to exposures to fenvalerate, flucythrinate, cypermethrin, deltapermethrin, and fluvalinate. Seizures have not been reported after exposure to permethrin. Pyrethroids may also cause paresthesias after skin contact. Paresthesias (stinging and numbness) usually begin 1-2 hours after contact and resolve within 24 hours. [EPA Pesticides, p. 87-8] Pyrethrins cause liver injury when fed to animals at high doses. [EXTOXNET]

Reference Link #1

Biomedical References

Reference Link #2

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)