4-Aminopyridine

Synonyms

Fampridine; 4-Pyridinamine; 4-Pyridylamine; p-Aminopyridine; gamma-Aminopyridine; Avitrol 200; Fampridine; 4-AP; Amino-4 pyridine; Avitrol [ChemIDplus]

Category

Avicides

Description

White crystals; [CAMEO] Formulated as grain bait or powder concentrate; [EXTOXNET]

Sources/Uses

Used as a chemical intermediate, a bird repellant, and a medication; [HSDB] A potassium channel blocker that is used primarily in research, but also in medicine to treat Lambert-Eaton syndrome and multiple sclerosis; [ChemIDplus] Used as an avicide, an intermediate, and textile dye fixative; [CAMEO]

Comments

"Material may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Material affects neural transmission. In sufficient concentrations, material may cause metabolic acidosis, respiratory arrest, and cardiac arrhythmias." [CAMEO] Effective bird repellant as flock is frightened by distress of poisoned birds; Avitrol is a central nervous system stimulant, and as little as 60 mg causes severe poisoning in adult humans. It is readily absorbed through the skin. Symptoms of poisoning include thirst, dizziness, weakness, sweating, toxic psychosis, tremors, and seizures. Avitrol can also cause methemoglobinemia. It is an eye irritant. [EXTOXNET]

Reference Link #1

Biomedical References

0.00034 mm Hg

Explanatory Notes

VP from ChemIDplus;

Reference Link #2

MetHgb is secondary toxic effect

Other CNS neurotoxin

Skin burns

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, acute toxic

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)