Comments
Causes somnolence, conjunctive irritation, corneal damage, and other cardiac and gastrointestinal changes in acute inhalation studies of cats; Causes lachrymation, general anesthesia, ataxia, dyspnea, respiratory depression, other liver changes, changes in renal tubules, and hemorrhage in acute inhalation studies of mice and rats; Causes impaired liver function tests, changes in renal tubules, emphysema, proteinuria, and changes in recordings from peripheral motor nerve in repeated-dose inhalation studies of rats; [RTECS] Decomposes above 25 deg C; A mild eye and mucous membrane irritant; [Merck Index] See "Nitromethane."