Urease

Synonyms

Enzyme urease; Urease enzyme preparation from Lactobacillus fermentum; Jack bean urease; [ChemIDplus] Urea amidohydrolase; [Merck Index] Urease, from Canavalia ensiformis (Jack bean); [Sigma-Aldrich MSDS]

Category

Enzymes

Description

Colorless solid; [Merck Index] Powder; [Sigma-Aldrich MSDS]

Sources/Uses

Nickel-dependent enzyme that hydrolyzes urea into ammonium carbonate; Used as a reagent to determine urea concentration in serum and other clinical samples; [Merck Index]

Comments

Causes somnolence, convulsions, and dyspnea in intravenous lethal-dose studies of rabbits; [RTECS] A skin and strong eye irritant; May cause respiratory sensitization; [Sigma-Aldrich MSDS] See "ENZYMES."

Biomedical References

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational