Acetylated myrcene

Synonyms

1,6-Octadiene, 7-methyl-3-methylene-, acetylated; [ChemIDplus]

Category

Esters, Other

Description

Liquid; [EPA ChAMP: Terpenoid Primary Alcohols and Related Esters - 2009]

Sources/Uses

Used in odor and flavoring agents; [EPA ChAMP: Terpenoid Primary Alcohols and Related Esters - 2009]

Comments

Category members and supporting chemicals demonstrate low acute toxicity by oral and dermal exposure; Moderate to severe skin irritation in humans and experimental animals; Eye irritation in rabbits; Skin sensitization in humans and mice; No systemic toxicity in 112-day and 17-week oral studies of rats at the highest tested doses (approximately 500 mg/kg/day); Mortality, stomach lesions, and cytoplasmic vacuolization of the liver, kidney, and myocardium in 13-week oral study of mice (LOAEL of 2,000 mg/kg/day); A mixture of terpenoid esters and alcohols, with the majority (60-65%) being geranyl and neryl acetates; [EPA ChAMP: Terpenoid Primary Alcohols and Related Esters - 2009] See "Geranyl acetate" and "Geraniol."

Reference Link #1

Biomedical References

Yes

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic