3,4,5,3',4'-Pentachlorobiphenyl
Agent Name
3,4,5,3',4'-Pentachlorobiphenyl
CAS Number
57465-28-8
Formula
C12-H5-Cl5
Major Category
Other Classes
Synonyms
3,3',4,4',5-Pentachloro-1,1'-biphenyl; 3,3',4,4',5-Pentachlorobiphenyl; 3,4,3',4',5'-Pentachlorobiphenyl; 3,4,5,3',4'-Penta coplanar polychlorinated biphenyl; PCB 126; 1,1'-Biphenyl, 3,3',4,4',5-pentachloro-; [ChemIDplus] UN3432
Category
Halogenated Polyaromatics
Description
White solid; [Cerilliant MSDS]
Comments
Clear evidence of carcinogenicity in female rats; [NTP] Classified as Group 1 based on animal evidence and mechanistic data (strong evidence for an aryl hydrocarbon receptor) without epidemiological evidence; [IARC 2012] May have cumulative adverse effects; Targets the liver, kidney, CNS, and skin; [Cerilliant MSDS] See "Polychlorinated biphenyls" and linked occupational disease.
Reference Link #1
Biomedical References
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Reproductive Toxin
Yes
Dermatotoxin
Chloracne
IARC Carcinogen
Established
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: