Dipropylene glycol methyl ether acetate

Synonyms

DPGMA; [Glycol Ethers Online] DPMA; [OECD SIDS: Propylene Glycol Ethers - 2003] Propanol, 1 (or 2)-(2-methoxymethylethoxy)-, acetate; [ChemIDplus]

Category

Glycol Ethers (P Series)

Sources/Uses

Used as an active and tailing solvent in coatings and a solvent in silkscreen printing inks; [OECD SIDS: Propylene Glycol Ethers - 2003]

Comments

Commercial product is a mixture of up to 4 isomers due to the position of the internal ether being linked to either the primary or secondary carbon atoms; Category members demonstrate LOAELs of 1,000 mg/kg/day (highest tested dose) in 13-week oral studies of rats for increased liver and kidney weight without corresponding histopathology; No hematotoxicity observed; Eye and nasal mucosa irritation and increased liver weights, some with corresponding histopathology, in 2-week inhalation studies of rats; [OECD SIDS: Propylene Glycol Ethers - 2003]

Biomedical References

0.12 mm Hg

LC50 (rat) > 5,700 mg/m3

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Painting (Solvents)
• Silk-Screen Printing