Dipropylene glycol mono-tert-butyl ether

Synonyms

DPtBGE; [Glycol Ethers Online] Propanol, (2-(1,1-dimethylethoxy)methylethoxy)-; [ChemIDplus] DPGTBE; [ECETOC] Di(propylene glycol) tert-butyl ether, mixture of isomers; [Sigma-Aldrich MSDS] UN1993

Category

Glycol Ethers (P Series)

Description

Colorless liquid; [Sigma-Aldrich MSDS]

Comments

Not a skin irritant in rabbits; Causes eye irritation with reversible corneal opacity in rabbits (at 72 hours but resolved by day 7); Not a skin sensitizer in guinea pigs using the maximization test; Increased liver and kidney weights with minor centrilobular hepatocyte enlargement observed in 14-day oral study of rats at 300 and 1,000 mg/kg/day; Effects on the liver and adrenal gland observed in 13-week oral study of rats (fully recovered following 4-week recovery period); No evidence of neurotoxicity or mutagenicity; [ToxPlanet: ECETOC, 4th ed., Vol. 2] A skin and strong eye irritant; [Sigma-Aldrich MSDS]

Biomedical References

0.32 mm Hg

LC50 (rat) > 5,110 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Combustible liquid, n.o.s."

Acute solvent syndrome

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect