Phenylglycine acid chloride hydrochloride

Synonyms

(-)-alpha-(Chloroformyl)benzylammonium chloride; Benzeneacetyl chloride, alpha-amino-, hydrochloride (1:1),(alphaR)-; Benzeneacetyl chloride, alpha-amino-, hydrochloride,(alphaR)-; (R)-alpha-Aminobenzeneacetyl chloride, hydrochloride; D-(-)-Phenylglycine acid chloride, hydrochloride; [ChemIDplus] (R)-(-)-2-Phenylglycine chloride hydrochloride; D-(-)-alpha-Phenylglycine chloride hydrochloride; [Sigma-Aldrich MSDS] UN3261

Category

Pharmaceuticals

Description

Solid; Readily hydrolyzes in water to D-phenylglycine; [IUCLID] Light brown powder; [Sigma-Aldrich MSDS]

Sources/Uses

An intermediate in the production of ampicillin; [Reference #1]

Comments

Corrosive to skin (rabbit); EC classification: not irritating; Risk of serious damage to eyes; Skin and respiratory sensitization reported in humans; [IUCLID] Occupational asthma confirmed in 29% of pharmaceutical workers; [Malo] Causes burns and lachrymation; Inhalation may cause corrosive injuries to upper respiratory tract; [Sigma-Aldrich MSDS] See "Ampicillin."

Reference Link #1

Biomedical References

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Corrosive solid, acidic, organic, n.o.s."

Yes

Skin burns

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational