1,3-Diisopropenylbenzene
Agent Name
1,3-Diisopropenylbenzene
CAS Number
3748-13-8
Formula
C12-H14
Major Category
Other Classes
Synonyms
1,3-Bis(1-methylethenyl)benzene; Benzene, m-diisopropenyl-; m-Diisopropenylbenzene; m-DIPEB; Benzene, 1,3-bis(1-methylethenyl)-; m-Bis(1-methylvinyl)benzene; [ChemIDplus]
Category
Aromatic Hydrocarbons
Description
Liquid; [EPA ChAMP: Initial Risk-Based Prioritization] Clear light yellow liquid; [Sigma-Aldrich MSDS]
Sources/Uses
Used as an intermediate for other basic chemicals, diisocyanate monomers, and optical products; [EPA ChAMP: Initial Risk-Based Prioritization]
Comments
A mild skin and eye irritant in rabbits; A skin sensitizer in guinea pigs; No systemic, reproductive, or developmental toxicity observed in oral study of rats at doses up to 1,000 mg/kg/day; Increased absolute and relative liver weights (increased serum enzymes indicative of liver toxicity but without corresponding histopathology) observed in 4-week inhalation study of rats at 970 mg/m3/6hrs/day; [EPA ChAMP: Initial Risk-Based Prioritization] An irritant; May cause skin sensitization; [ECHA REACH Registrations] A skin and strong eye irritant; [Sigma-Aldrich MSDS] Search for (3748-13-8[EC/RN Number]) AND (sensitizer OR sensitization OR dermatitis OR allergic): no results; [PubMed]
Biomedical References
Exposure Assessment
Vapor Pressure
0.16 mm Hg
Lethal Concentration
LC50 (rat) = 540-5,600 mg/m3/6hr
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.