Cadaverine
Agent Name
Cadaverine
CAS Number
462-94-2
Formula
C5-H14-N2
Major Category
Nitrogen Compounds
Synonyms
1,5-Diaminopentane; 1,5-Pentamethylenediamine; Animal coniine; Cadaverin; Pentamethylenediamine; 1,5-Pentanediamine; [ChemIDplus] UN2735
Category
Amines, Aliphatic
Description
Colorless syrupy liquid that fumes in air; mp = 9 deg C; [Merck Index] Colorless hygroscopic liquid with an amine-like odor; [Alfa Aesar MSDS]
Sources/Uses
"A foul-smelling diamine formed by bacterial decarboxylation of lysine." [ChemIDplus] Biogenic polyamine present in cholera discharge; [Merck Index] Formed from decay of animal proteins; Used to make high polymers, as an intermediate, and in biological research; [HSDB] "Cadaverine is a foul-smelling diamine compound produced by protein hydrolysis during putrefaction of animal tissue." [Wikipedia]
Comments
A strong base that attracts carbon dioxide; A skin irritant and possible sensitizer; [Merck Index] Causes burns; [HSDB] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS] Search for (462-94-2[EC/RN Number]) AND (sensitizer OR sensitization OR allergic OR dermatitis): no papers confirming skin sensitization; [PubMed] See "1,6-Diaminohexane."
Biomedical References
Exposure Assessment
Vapor Pressure
1.01 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Polyamines, liquid, corrosive, n.o.s."
NFPA
high ambient temp required
Adverse Effects
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.