2-Ethylhexyl nitrate

Agent Name
2-Ethylhexyl nitrate
CAS Number
27247-96-7
Formula
C8-H17-N-O3
Major Category
Nitrogen Compounds
2-Ethylhexyl nitrate formula graphical representation
Synonyms
Ethylhexyl nitrate; Nitronal; Nitric acid, 2-ethylhexyl ester; [ChemIDplus] "Ethyl" Diesel Ignition Improver 3 ("Ethyl" DII-3); 2-EHN; 3-Nitro-oxymethylheptane; Du Pont Diesel Additive 1000; DU PONT DIESEL ADDITIVE 1000; ECA 8478; ETHYL DII-3; Exchem GO-1 Cetane Improver; EXCHEM GO-1 CETANE IMPROVER; EXXON ECA 8478; HITEC 4103; HiTec 4103 Fuel Additive; NEH; NITRATE D'ETHYL-2 HEXYLE; Nitric acid, 2-ethylhexyl ester of; NITRIC ACID, 2-ETHYLHEXYL ESTER; Octel CI-0801 Cetane Number Improver; OCTEL CI-0801 CETANE NUMBER IMPROVER; OCTYL NITRATE; PROCETANE; [IUCLID] UN1993
Category
Nitrates and Nitrites
Description
Light yellow liquid with a pleasant odor; [CAMEO] Colorless liquid; [Sigma-Aldrich MSDS]
Sources/Uses
Used in chemical manufacture; [CAMEO] Used as a diesel fuel additive and solvent; [REPROTOX] Used as an additive in diesel fuels to improve ignition and raise the cetane number; [EPA ChAMP: Submission]
Comments
Can cause headaches from dermal or inhalation exposure; [IUCLID] Causes little or no eye irritation in rabbits; Not a skin sensitizer in guinea pig maximization tests; Increased mean liver weight and polycythemia observed in 14-day inhalation study of rats at concentrations greater than 42 ppm; [IUCLID] Irritation but no systemic toxicity observed in 21-day dermal study of rabbits at doses up to 500 mg/kg/day; A 28-day oral study of rats produced changes in urinary parameters, significantly increased liver and kidney weights, and a NOEL of 20 mg/kg/day; [EPA ChAMP: Submission] May cause irritation; Harmful by ingestion, inhalation, and skin absorption; [Sigma-Aldrich MSDS] See "Amyl nitrate."
Biomedical References

Exposure Assessment

Vapor Pressure
0.035 mm Hg
Lethal Concentration
LC50 (rat) > 14,000 mg/m3/4hr
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Combustible liquid, n.o.s."

Adverse Effects

Methemoglobinemia
MetHgb is secondary toxic effect

Diseases, Processes, and Activities Linked to This Agent

Other Information
No other related information on this agent was found.